Wales could be without Rhys Webb and Leigh Halfpenny at the World Cup after they came off on stretchers in their 23-19 warm up win over Italy.
Webb, 26, suffered ankle damage at a first-half breakdown at Millennium Stadium in Cardiff.
Halfpenny damaged his right knee in the 70th minute.
Wales coach Warren Gatland said: “They don’t look too good at the moment, but we’ll just have to wait and see.”
Webb underwent a scan on Saturday night and Halfpenny will do the same on Monday.
Gatland said Webb’s injury was “not a break, but could be ligament damage”.
He added: “If the injuries are bad we might have to bring in players, but we won’t know until next week.
“You have to feel for them if they are ruled out. It’s a massive blow for them and disappointing for us.”
Webb has established himself as Wales’ leading half-back while 26-year-old Halfpenny is their main goal-kicker.
If Webb is ruled out, Racing 92 veteran Mike Phillips is a leading candidate to be recalled, having been omitted from the original 31-man squad.